BDBM81962 S-L-365,260
SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1
InChI Key InChIKey=KDFQABSFVYLGPM-QFIPXVFZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 25 hits for monomerid = 81962
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition by displacing [3H]CCK-8S against human Cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:The compound was evaluated for the inhibition of binding of [3H]-PD 140376 to Cholecystokinin type B receptor in guinea pig cortex.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Compound was tested for the affinity against Cholecystokinin type B receptor on guinea pig cortex.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]pCCK-8 from cholecystokinin type B receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type B receptor of guinea pigMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Tested for its receptor affinity from competition with 20 pM [125I]BH-CCK-8S for Cholecystokinin type B receptor binding sites in mouse cortical homo...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of binding of [125I]CCK-8S to Cholecystokinin type B receptor in mouse cerebral cortex homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Affinity of compound on binding of [3H]pCCK-8 to the cholecystokinin type B receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Compound was tested for binding affinity against rat brain Cholecystokinin type B receptor expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 269nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type B receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of binding of [125I]gastrin to Cholecystokinin type B receptor from guinea pig gastric glandsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Evaluated for inhibition of cholecystokinin type B receptor by displacing [125I]-Bolton hunter CCK-8 radioligand in the mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to mouse cerebral cortex cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Binding activity against Cholecystokinin type B receptor from guinea pig cortex using [125]BH CCK-8s as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of inositol phosphate production induced by Cholecystokinin type B receptor (0.5 nM)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Half maximal inhibition of specific binding of [125I]Bolton-Hunter CCK-8 to Cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Cholecystokinin type B receptor induced guinea pig gall bladder contractions when given intravenouslyMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against gastrin receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glandsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Displacement of CCK-8 from human Cholecystokinin type B receptor expressing CHO cell membranes More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonistic activity against cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibitory concentration against Cholecystokinin B receptorMore data for this Ligand-Target Pair